A carregar...

C (3)-symmetric opioid scaffolds are pH-responsive DNA condensation agents

Herein we report the synthesis of tripodal C(3)-symmetric opioid scaffolds as high-affinity condensation agents of duplex DNA. Condensation was achieved on both supercoiled and canonical B-DNA structures and identified by agarose electrophoresis, viscosity, turbidity and atomic force microscopy (AFM...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: McStay, Natasha, Molphy, Zara, Coughlan, Alan, Cafolla, Attilio, McKee, Vickie, Gathergood, Nicholas, Kellett, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314759/
https://ncbi.nlm.nih.gov/pubmed/27899572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1097
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!