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Triggering autophagic cell death with a di-manganese(II) developmental therapeutic

There is an unmet need for novel metal-based chemotherapeutics with alternative modes of action compared to clinical agents such as cisplatin and metallo-bleomycin. Recent attention in this field has focused on designing intracellular ROS-mediators as powerful cytotoxins of human cancers and identif...

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Detalhes bibliográficos
Publicado no:Redox Biol
Principais autores: Slator, Creina, Molphy, Zara, McKee, Vickie, Kellett, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5328722/
https://ncbi.nlm.nih.gov/pubmed/28236767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.01.024
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