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Di-copper metallodrugs promote NCI-60 chemotherapy via singlet oxygen and superoxide production with tandem TA/TA and AT/AT oligonucleotide discrimination

In order to expand the current repertoire of cancer treatments and to help circumvent limitations associated with resistance, the identification of new metallodrugs with high potency and novel mechanisms of action is of significant importance. Here we present a class of di-copper(II) complex based o...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Slator, Creina, Molphy, Zara, McKee, Vickie, Long, Conor, Brown, Tom, Kellett, Andrew
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5888725/
https://ncbi.nlm.nih.gov/pubmed/29474633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky105
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