NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway

Mitochondrial bioenergetics are critical for cellular homeostasis and stress responses. The reactive oxygen species-generating enzyme, NADPH oxidase 4 (Nox4), regulates a number of physiological and pathological processes, including cellular differentiation, host defense, and tissue fibrosis. In thi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Biol Chem
Egile Nagusiak: Bernard, Karen, Logsdon, Naomi J., Miguel, Veronica, Benavides, Gloria A., Zhang, Jianhua, Carter, A. Brent, Darley-Usmar, Victor M., Thannickal, Victor J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2017
Gaiak:
Cell Biology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314196/
https://ncbi.nlm.nih.gov/pubmed/28049732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.752261
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