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Inducible and Naturally Occurring T Regulatory Cells Enhance Lung Allergic Responses Via Divergent Transcriptional Pathways

BACKGROUND: T regulatory cells attenuate development of asthma in wild-type (WT) mice with both naturally occurring (nTregs) and inducible T regulatory cells (iTregs) exhibiting suppressive activity. When transferred into CD8-deficient (CD8(−/−)) recipients, both cell types enhanced development of a...

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Detalhes bibliográficos
Publicado no:J Allergy Clin Immunol
Main Authors: Joetham, Anthony, Schedel, Michaela, O’Connor, Brian P., Kim, Soohyun, Takeda, Katsuyuki, Abbott, Jordan, Gelfand, Erwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313386/
https://ncbi.nlm.nih.gov/pubmed/27542981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2016.06.051
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