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JNK2 Regulates the Functional Plasticity of Naturally Occurring T Regulatory Cells and the Enhancement of Lung Allergic Responses

Glucocorticoid-induced TNFR family-related protein (GITR)-mediated activation of c-Jun N-terminal kinase (JNK) was shown to regulate the suppressive activity of naturally occurring CD4(+)CD25(+) T regulatory cells (nTregs) in wild-type (WT) hosts. Here, CD4(+)CD25(+) T cells were shown capable of be...

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Detalhes bibliográficos
Main Authors: Joetham, Anthony, Schedel, Michaela, Takeda, Katsuyuki, Jia, Yi, Ashino, Shigeru, Dakhama, Azzeddine, Lluis, Anna, Okamoto, Masakazu, Gelfand, Erwin W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135003/
https://ncbi.nlm.nih.gov/pubmed/25070841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400604
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