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Accessing Alternative Reaction Pathways of the Intermolecular Condensation between Homo-Propargyl Alcohols and Terminal Alkynes through Divergent Gold Catalysis

An intermolecular condensation of alkynols and terminal alkynes is reported. Using IPrAuNTf(2), an efficient Au-catalyzed cyclization-alkynylation strategy furnishes (2-arylalkynyl) cyclic ethers in moderate to excellent yields (up to 94%). This strategy is extended to the synthesis of functionalize...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Smith, Courtney A., Motika, Stephen E., Wojtas, Lukasz, Shi, Xiaodong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313346/
https://ncbi.nlm.nih.gov/pubmed/28074975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6cc09794d
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