Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells

In breast cancer, a key feature of peritumoral adipocytes is their loss of lipid content observed both in vitro and in human tumors. The free fatty acids (FFAs), released by adipocytes after lipolysis induced by tumor secretions, are transferred and stored in tumor cells as triglycerides in lipid dr...

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Bibliografiske detaljer
Udgivet i:JCI Insight
Main Authors: Wang, Yuan Yuan, Attané, Camille, Milhas, Delphine, Dirat, Béatrice, Dauvillier, Stéphanie, Guerard, Adrien, Gilhodes, Julia, Lazar, Ikrame, Alet, Nathalie, Laurent, Victor, Le Gonidec, Sophie, Biard, Denis, Hervé, Caroline, Bost, Frédéric, Ren, Guo Sheng, Bono, Françoise, Escourrou, Ghislaine, Prentki, Marc, Nieto, Laurence, Valet, Philippe, Muller, Catherine
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313068/
https://ncbi.nlm.nih.gov/pubmed/28239646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87489
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