Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells

In breast cancer, a key feature of peritumoral adipocytes is their loss of lipid content observed both in vitro and in human tumors. The free fatty acids (FFAs), released by adipocytes after lipolysis induced by tumor secretions, are transferred and stored in tumor cells as triglycerides in lipid dr...

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發表在:JCI Insight
Main Authors: Wang, Yuan Yuan, Attané, Camille, Milhas, Delphine, Dirat, Béatrice, Dauvillier, Stéphanie, Guerard, Adrien, Gilhodes, Julia, Lazar, Ikrame, Alet, Nathalie, Laurent, Victor, Le Gonidec, Sophie, Biard, Denis, Hervé, Caroline, Bost, Frédéric, Ren, Guo Sheng, Bono, Françoise, Escourrou, Ghislaine, Prentki, Marc, Nieto, Laurence, Valet, Philippe, Muller, Catherine
格式: Artigo
語言:Inglês
出版: American Society for Clinical Investigation 2017
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5313068/
https://ncbi.nlm.nih.gov/pubmed/28239646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87489
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