Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from PPAT support the directed migration of prostate cancer cells and that this event is strongly promoted by obesity. This p...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Laurent, Victor, Guérard, Adrien, Mazerolles, Catherine, Le Gonidec, Sophie, Toulet, Aurélie, Nieto, Laurence, Zaidi, Falek, Majed, Bilal, Garandeau, David, Socrier, Youri, Golzio, Muriel, Cadoudal, Thomas, Chaoui, Karima, Dray, Cedric, Monsarrat, Bernard, Schiltz, Odile, Wang, Yuan Yuan, Couderc, Bettina, Valet, Philippe, Malavaud, Bernard, Muller, Catherine
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729927/
https://ncbi.nlm.nih.gov/pubmed/26756352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10230
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