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Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity

Obesity favours the occurrence of locally disseminated prostate cancer in the periprostatic adipose tissue (PPAT) surrounding the prostate gland. Here we show that adipocytes from PPAT support the directed migration of prostate cancer cells and that this event is strongly promoted by obesity. This p...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Laurent, Victor, Guérard, Adrien, Mazerolles, Catherine, Le Gonidec, Sophie, Toulet, Aurélie, Nieto, Laurence, Zaidi, Falek, Majed, Bilal, Garandeau, David, Socrier, Youri, Golzio, Muriel, Cadoudal, Thomas, Chaoui, Karima, Dray, Cedric, Monsarrat, Bernard, Schiltz, Odile, Wang, Yuan Yuan, Couderc, Bettina, Valet, Philippe, Malavaud, Bernard, Muller, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4729927/
https://ncbi.nlm.nih.gov/pubmed/26756352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10230
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