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SILAC-Based Proteomic Profiling of the Human MDA-MB-231 Metastatic Breast Cancer Cell Line in Response to the Two Antitumoral Lactoferrin Isoforms: The Secreted Lactoferrin and the Intracellular Delta-Lactoferrin

BACKGROUND: Lactoferrins exhibit antitumoral activities either as a secretory lactoferrin or an intracellular delta-lactoferrin isoform. These activities involve processes such as regulation of the cell cycle and apoptosis. While lactoferrin has been shown to exert its function by activating differe...

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Detalhes bibliográficos
Main Authors: Hoedt, Esthelle, Chaoui, Karima, Huvent, Isabelle, Mariller, Christophe, Monsarrat, Bernard, Burlet-Schiltz, Odile, Pierce, Annick
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4130549/
https://ncbi.nlm.nih.gov/pubmed/25116916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0104563
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