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Structure, kinetic characterization and subcellular localization of the two ribulose 5-phosphate epimerase isoenzymes from Trypanosoma cruzi

The enzyme of the pentose phosphate pathway (PPP) ribulose-5-phosphate-epimerase (RPE) is encoded by two genes present in the genome of Trypanosoma cruzi CL Brener clone: TcRPE1 and TcRPE2. Despite high sequence similarity at the amino acid residue level, the recombinant isoenzymes show a strikingly...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Gonzalez, Soledad Natalia, Valsecchi, Wanda Mariela, Maugeri, Dante, Delfino, José María, Cazzulo, Juan José
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312968/
https://ncbi.nlm.nih.gov/pubmed/28207833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0172405
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