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Ribose 5-phosphate isomerase type B from Trypanosoma cruzi: kinetic properties and site-directed mutagenesis reveal information about the reaction mechanism

Trypanosoma cruzi, the human parasite that causes Chagas disease, contains a functional pentose phosphate pathway, probably essential for protection against oxidative stress and also for R5P (ribose 5-phosphate) production for nucleotide synthesis. The haploid genome of the CL Brener clone of the pa...

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Detalhes bibliográficos
Main Authors: Stern, Ana L., Burgos, Emmanuel, Salmon, Laurent, Cazzulo, Juan J.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698680/
https://ncbi.nlm.nih.gov/pubmed/16981853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061049
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