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A single mutation in the envelope protein modulates flavivirus antigenicity, stability, and pathogenesis
The structural flexibility or ‘breathing’ of the envelope (E) protein of flaviviruses allows virions to sample an ensemble of conformations at equilibrium. The molecular basis and functional consequences of virus conformational dynamics are poorly understood. Here, we identified a single mutation at...
Gorde:
| Argitaratua izan da: | PLoS Pathog |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2017
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5312798/ https://ncbi.nlm.nih.gov/pubmed/28207910 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006178 |
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