The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF- kappaB activation

BACKGROUND: Infection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA. This activates DNA damage response (DDR) signaling including induction of e...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Virol J
Egile Nagusiak: White, Martyn K., Bellizzi, Anna, Ibba, Gabriele, Pietropaolo, Valeria, Palamara, Anna T., Wollebo, Hassen S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2017
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312431/
https://ncbi.nlm.nih.gov/pubmed/28202068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0707-7
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