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CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection.

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS) caused by reactivation of the human polyomavirus JCV gene expression and its replication in oligodendrocytes, the myelin producing cells in the brain. Once a rare disease seen in pat...

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Bibliografiske detaljer
Main Authors: Hassen S Wollebo, Anna Bellizzi, Rafal Kaminski, Wenhui Hu, Martyn K White, Kamel Khalili
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4567079?pdf=render
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