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CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS) caused by reactivation of the human polyomavirus JCV gene expression and its replication in oligodendrocytes, the myelin producing cells in the brain. Once a rare disease seen in pat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Wollebo, Hassen S., Bellizzi, Anna, Kaminski, Rafal, Hu, Wenhui, White, Martyn K., Khalili, Kamel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567079/
https://ncbi.nlm.nih.gov/pubmed/26360417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136046
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