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CRISPR/Cas9 System as an Agent for Eliminating Polyomavirus JC Infection

Progressive multifocal leukoencephalopathy (PML) is a fatal demyelinating disease of the central nervous system (CNS) caused by reactivation of the human polyomavirus JCV gene expression and its replication in oligodendrocytes, the myelin producing cells in the brain. Once a rare disease seen in pat...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Wollebo, Hassen S., Bellizzi, Anna, Kaminski, Rafal, Hu, Wenhui, White, Martyn K., Khalili, Kamel
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567079/
https://ncbi.nlm.nih.gov/pubmed/26360417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136046
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