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Suppression of c-Myc and RRM2 expression in pancreatic cancer cells by the sphingosine kinase-2 inhibitor ABC294640

Pancreatic cancer remains extremely difficult to treat, with the average lifespan following diagnosis being only 3-6 months, resulting in a death to incidence ratio of 0.94. A major reason for this high mortality rate is resistance to the main chemotherapeutic agent used to treat this disease, gemci...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Lewis, Clayton S., Voelkel-Johnson, Christina, Smith, Charles D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312377/
https://ncbi.nlm.nih.gov/pubmed/27517489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11112
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