Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

Exosomes are small (30-100nm) vesicles secreted from all cell types serving as inter-cell communicators and affecting biological processes in “recipient” cells upon their uptake. The current study demonstrates for the first time that hTERT mRNA, the transcript of the enzyme telomerase, is shuttled f...

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Publicat a:Oncotarget
Autors principals: Gutkin, Anna, Uziel, Orit, Beery, Einat, Nordenberg, Jardena, Pinchasi, Maria, Goldvaser, Hadar, Henick, Steven, Goldberg, Michal, Lahav, Meir
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312303/
https://ncbi.nlm.nih.gov/pubmed/27385095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10384
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