Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

Exosomes are small (30-100nm) vesicles secreted from all cell types serving as inter-cell communicators and affecting biological processes in “recipient” cells upon their uptake. The current study demonstrates for the first time that hTERT mRNA, the transcript of the enzyme telomerase, is shuttled f...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Gutkin, Anna, Uziel, Orit, Beery, Einat, Nordenberg, Jardena, Pinchasi, Maria, Goldvaser, Hadar, Henick, Steven, Goldberg, Michal, Lahav, Meir
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312303/
https://ncbi.nlm.nih.gov/pubmed/27385095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10384
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