Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

Exosomes are small (30-100nm) vesicles secreted from all cell types serving as inter-cell communicators and affecting biological processes in “recipient” cells upon their uptake. The current study demonstrates for the first time that hTERT mRNA, the transcript of the enzyme telomerase, is shuttled f...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Gutkin, Anna, Uziel, Orit, Beery, Einat, Nordenberg, Jardena, Pinchasi, Maria, Goldvaser, Hadar, Henick, Steven, Goldberg, Michal, Lahav, Meir
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312303/
https://ncbi.nlm.nih.gov/pubmed/27385095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10384
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