Tumor cells derived exosomes contain hTERT mRNA and transform nonmalignant fibroblasts into telomerase positive cells

Exosomes are small (30-100nm) vesicles secreted from all cell types serving as inter-cell communicators and affecting biological processes in “recipient” cells upon their uptake. The current study demonstrates for the first time that hTERT mRNA, the transcript of the enzyme telomerase, is shuttled f...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Gutkin, Anna, Uziel, Orit, Beery, Einat, Nordenberg, Jardena, Pinchasi, Maria, Goldvaser, Hadar, Henick, Steven, Goldberg, Michal, Lahav, Meir
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312303/
https://ncbi.nlm.nih.gov/pubmed/27385095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10384
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