Co-expression modules of NF1, PTEN and sprouty enable distinction of adult diffuse gliomas according to pathway activities of receptor tyrosine kinases

Inter-individual variability causing elevated signaling of receptor tyrosine kinases (RTK) may have hampered the efficacy of targeted therapies. We developed a molecular signature for clustering adult diffuse gliomas based on the extent of RTK pathway activities. Glioma gene modules co-expressed wit...

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Udgivet i:Oncotarget
Main Authors: Zhang, Wanyu, Lv, Yuhong, Xue, Yang, Wu, Chenxing, Yao, Kun, Zhang, Chuanbao, Jin, Qiang, Huang, Rong, Li, Jiuyi, Sun, Yingyu, Su, Xiaodong, Jiang, Tao, Fan, Xiaolong
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312298/
https://ncbi.nlm.nih.gov/pubmed/27385209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10359
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