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Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapy
Gliomas are the most common and deadly form of malignant primary brain tumors. Loss of the tumor-suppressor PTEN and activation of the receptor tyrosine kinases (RTKs) EGF receptor, c-Met, PDGF receptor and VEGF receptor are among the most common molecular dysfunctions associated with glioma maligna...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2678856/ https://ncbi.nlm.nih.gov/pubmed/19192961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/14737140.9.2.235 |
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