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FGFR3, as a receptor tyrosine kinase, is associated with differentiated biological functions and improved survival of glioma patients

BACKGROUND: Activation of receptor tyrosine kinases is common in Malignancies. FGFR3 fusion with TACC3 has been reported to have transforming effects in primary glioblastoma and display oncogenic activity in vitro and in vivo. We set out to investigate the role of FGFR3 in glioma through transcripto...

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Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Wang, Zheng, Zhang, Chuanbao, Sun, Lihua, Liang, Jingshan, Liu, Xing, Li, Guanzhang, Yao, Kun, Zhang, Wei, Jiang, Tao
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5356683/
https://ncbi.nlm.nih.gov/pubmed/27829236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13139
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