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Glucocorticoid Receptor-Targeted Liposomal Codelivery of Lipophilic Drug and Anti-Hsp90 Gene: Strategy to Induce Drug-Sensitivity, EMT-Reversal, and Reduced Malignancy in Aggressive Tumors

Many cancers including the late stage ones become drug-resistant and undergo epithelial-to-mesenchymal transition (EMT). These lead to enhanced invasion, migration, and metastasis toward manifesting its aggressiveness and malignancy. One of the key hallmarks of cancer is its overdependence on glycol...

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Détails bibliographiques
Publié dans:Mol Pharm
Auteurs principaux: Mondal, Sujan Kumar, Jinka, Sudhakar, Pal, Krishnendu, Nelli, Swetha, Dutta, Shamit Kumar, Wang, Enfeng, Ahmad, Ajaz, AlKharfy, Khalid M., Mukhopadhyay, Debabrata, Banerjee, Rajkumar
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312262/
https://ncbi.nlm.nih.gov/pubmed/27184196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.6b00230
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