PAK4 interacts with p85 alpha: implications for pancreatic cancer cell migration

It has been reported that p21-activated kinase 4 (PAK4) is amplified in pancreatic cancer tissue. PAK4 is a member of the PAK family of serine/threonine kinases, which act as effectors for several small GTPases, and has been specifically identified to function downstream of HGF-mediated c-Met activa...

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Udgivet i:Sci Rep
Main Authors: King, Helen, Thillai, Kiruthikah, Whale, Andrew, Arumugam, Prabhu, Eldaly, Hesham, Kocher, Hemant M., Wells, Claire M.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312077/
https://ncbi.nlm.nih.gov/pubmed/28205613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42575
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