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Deciphering the link between PI3K and PAK: An opportunity to target key pathways in pancreatic cancer?

The development of personalised therapies has ushered in a new and exciting era of cancer treatment for a variety of solid malignancies. Yet pancreatic ductal adenocarcinoma (PDAC) has failed to benefit from this paradigm shift, remaining notoriously refractory to targeted therapies. Chemotherapy is...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Thillai, Kiruthikah, Lam, Hoyin, Sarker, Debashis, Wells, Claire M.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5355171/
https://ncbi.nlm.nih.gov/pubmed/27845911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.13309
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