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Integrin αvβ6 Critically Regulates Hepatic Progenitor Cell Function and Promotes Ductular Reaction, Fibrosis, and Tumorigenesis

Integrin αvβ6 is rapidly up-regulated on cells of epithelial lineage during tissue injury, where one of its primary functions is activation of latent transforming growth factor beta 1 (TGFβ1). In human liver cirrhosis, αvβ6 is overexpressed by cells comprising the ductular reaction, and its inhibiti...

詳細記述

保存先:
書誌詳細
出版年:Hepatology
主要な著者: Peng, Zhen-Wei, Ikenaga, Naoki, Liu, Susan B., Sverdlov, Deanna Y., Vaid, Kahini A., Dixit, Richa, Weinreb, Paul H., Violette, Shelia, Sheppard, Dean, Schuppan, Detlef, Popov, Yury
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312042/
https://ncbi.nlm.nih.gov/pubmed/26448099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28274
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