Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

Plants and many lower organisms, but not mammals, express alternative oxidases (AOXs) that branch the mitochondrial respiratory chain, transferring electrons directly from ubiquinol to oxygen without proton pumping. Thus, they maintain electron flow under conditions when the classical respiratory ch...

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Publicado en:Dis Model Mech
Autores principales: Szibor, Marten, Dhandapani, Praveen K., Dufour, Eric, Holmström, Kira M., Zhuang, Yuan, Salwig, Isabelle, Wittig, Ilka, Heidler, Juliana, Gizatullina, Zemfira, Gainutdinov, Timur, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Nandania, Jatin, Velagapudi, Vidya, Wietelmann, Astrid, Rustin, Pierre, Gellerich, Frank N., Jacobs, Howard T., Braun, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312010/
https://ncbi.nlm.nih.gov/pubmed/28067626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027839
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