Broad AOX expression in a genetically tractable mouse model does not disturb normal physiology

Plants and many lower organisms, but not mammals, express alternative oxidases (AOXs) that branch the mitochondrial respiratory chain, transferring electrons directly from ubiquinol to oxygen without proton pumping. Thus, they maintain electron flow under conditions when the classical respiratory ch...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Szibor, Marten, Dhandapani, Praveen K., Dufour, Eric, Holmström, Kira M., Zhuang, Yuan, Salwig, Isabelle, Wittig, Ilka, Heidler, Juliana, Gizatullina, Zemfira, Gainutdinov, Timur, Fuchs, Helmut, Gailus-Durner, Valérie, de Angelis, Martin Hrabě, Nandania, Jatin, Velagapudi, Vidya, Wietelmann, Astrid, Rustin, Pierre, Gellerich, Frank N., Jacobs, Howard T., Braun, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5312010/
https://ncbi.nlm.nih.gov/pubmed/28067626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.027839
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