Cytosolic, but not matrix, calcium is essential for adjustment of mitochondrial pyruvate supply

Mitochondrial oxidative phosphorylation (OXPHOS) and cellular workload are tightly balanced by the key cellular regulator, calcium (Ca(2+)). Current models assume that cytosolic Ca(2+) regulates workload and that mitochondrial Ca(2+) uptake precedes activation of matrix dehydrogenases, thereby match...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Szibor, Marten, Gizatullina, Zemfira, Gainutdinov, Timur, Endres, Thomas, Debska-Vielhaber, Grazyna, Kunz, Matthias, Karavasili, Niki, Hallmann, Kerstin, Schreiber, Frank, Bamberger, Alexandra, Schwarzer, Michael, Doenst, Torsten, Heinze, Hans-Jochen, Lessmann, Volkmar, Vielhaber, Stefan, Kunz, Wolfram S., Gellerich, Frank N.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7135991/
https://ncbi.nlm.nih.gov/pubmed/32094224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.011902
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