FocusHeuristics – expression-data-driven network optimization and disease gene prediction

To identify genes contributing to disease phenotypes remains a challenge for bioinformatics. Static knowledge on biological networks is often combined with the dynamics observed in gene expression levels over disease development, to find markers for diagnostics and therapy, and also putative disease...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Ernst, Mathias, Du, Yang, Warsow, Gregor, Hamed, Mohamed, Endlich, Nicole, Endlich, Karlhans, Murua Escobar, Hugo, Sklarz, Lisa-Madeleine, Sender, Sina, Junghanß, Christian, Möller, Steffen, Fuellen, Georg, Struckmann, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311990/
https://ncbi.nlm.nih.gov/pubmed/28205611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42638
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