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FocusHeuristics – expression-data-driven network optimization and disease gene prediction

To identify genes contributing to disease phenotypes remains a challenge for bioinformatics. Static knowledge on biological networks is often combined with the dynamics observed in gene expression levels over disease development, to find markers for diagnostics and therapy, and also putative disease...

Полное описание

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Ernst, Mathias, Du, Yang, Warsow, Gregor, Hamed, Mohamed, Endlich, Nicole, Endlich, Karlhans, Murua Escobar, Hugo, Sklarz, Lisa-Madeleine, Sender, Sina, Junghanß, Christian, Möller, Steffen, Fuellen, Georg, Struckmann, Stephan
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311990/
https://ncbi.nlm.nih.gov/pubmed/28205611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42638
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