A common class of transcripts with 5′-intron depletion, distinct early coding sequence features, and N(1)-methyladenosine modification

Introns are found in 5′ untranslated regions (5′UTRs) for 35% of all human transcripts. These 5′UTR introns are not randomly distributed: Genes that encode secreted, membrane-bound and mitochondrial proteins are less likely to have them. Curiously, transcripts lacking 5′UTR introns tend to harbor sp...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Cenik, Can, Chua, Hon Nian, Singh, Guramrit, Akef, Abdalla, Snyder, Michael P., Palazzo, Alexander F., Moore, Melissa J., Roth, Frederick P.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2017
Assuntos:
Bioinformatics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311483/
https://ncbi.nlm.nih.gov/pubmed/27994090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.059105.116
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