N6-methyladenosine modification in a long non-coding RNA hairpin predisposes its conformation to protein binding

N6-methyladenosine (m(6)A) is a reversible and abundant internal modification of messenger RNA (mRNA) and long noncoding RNA (lncRNA) with roles in RNA processing, transport, and stability. Although m(6)A does not preclude Watson-Crick base pairing, the N6-methyl group alters the stability of RNA se...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Mol Biol
Auteurs principaux: Zhou, Katherine I., Parisien, Marc, Dai, Qing, Liu, Nian, Diatchenko, Luda, Sachleben, Joseph R., Pan, Tao
Format: Artigo
Langue:Inglês
Publié: 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4779075/
https://ncbi.nlm.nih.gov/pubmed/26343757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.08.021
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