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Synergistic functions of E2F7 and E2F8 are critical to suppress stress-induced skin cancer

E2F transcription factors are important regulators of the cell cycle, and unrestrained activation of E2F-dependent transcription is considered to be an important driver of tumor formation and progression. Although highly expressed in normal skin and skin cancer, the role of the atypical E2Fs, E2F7 a...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Thurlings, I, Martínez-López, L M, Westendorp, B, Zijp, M, Kuiper, R, Tooten, P, Kent, L N, Leone, G, Vos, H J, Burgering, B, de Bruin, A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5311251/
https://ncbi.nlm.nih.gov/pubmed/27452520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.251
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