Dose-dependent differences in the profile of mutations induced by an ultimate carcinogen from benzo[a]pyrene.

Mutations in the coding region of the hypoxanthine (guanine) phosphoribosyltransferase (HPRT) gene of Chinese hamster V-79 cells were examined after exposure of the cells to a high cytotoxic dose (0.48 microM; 35% survival) and a low noncytotoxic dose (0.04 microM; 100% survival) of the ultimate car...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Wei, S J, Chang, R L, Wong, C Q, Bhachech, N, Cui, X X, Hennig, E, Yagi, H, Sayer, J M, Jerina, D M, Preston, B D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53107/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1763036/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11227
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