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Influence of the selective antagonist of the NR2B subunit of the NMDA receptor, traxoprodil, on the antidepressant-like activity of desipramine, paroxetine, milnacipran, and bupropion in mice

Pre-clinical and clinical studies indicated that a blockade of the NMDA receptor complex creates new opportunities for the treatment of affective disorders, including depression. The aim of the present study was to assess the influence of traxoprodil (10 mg/kg) on the activity of desipramine (10 mg/...

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Publicado en:J Neural Transm (Vienna)
Main Authors: Stasiuk, Weronika, Szopa, Aleksandra, Serefko, Anna, Wyska, Elżbieta, Świąder, Katarzyna, Dudka, Jarosław, Wlaź, Piotr, Poleszak, Ewa
Formato: Artigo
Idioma:Inglês
Publicado: Springer Vienna 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310560/
https://ncbi.nlm.nih.gov/pubmed/27900470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00702-016-1657-8
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