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Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice

One of the newest substances, whose antidepressant activity was shown is traxoprodil, which is a selective antagonist of the NR2B subunit of the NMDA receptor. The main goal of the present study was to evaluate the effect of traxoprodil on animals’ behavior using the forced swim test (FST), as well...

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Detalhes bibliográficos
Publicado no:Metab Brain Dis
Main Authors: Poleszak, Ewa, Stasiuk, Weronika, Szopa, Aleksandra, Wyska, Elżbieta, Serefko, Anna, Oniszczuk, Anna, Wośko, Sylwia, Świąder, Katarzyna, Wlaź, Piotr
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933725/
https://ncbi.nlm.nih.gov/pubmed/26924124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11011-016-9810-5
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