DPCPX, a selective adenosine A1 receptor antagonist, enhances the antidepressant-like effects of imipramine, escitalopram, and reboxetine in mice behavioral tests

The main goal of the present study was to evaluate the influence of the adenosine A1 receptor (A1R) antagonist — DPCPX — on depressive-like behavior in mice, as well as the effect of DPCPX on the activity of imipramine, escitalopram, and reboxetine, each at non-effective doses. The influence of DPCP...

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Detalhes bibliográficos
Publicado no:Naunyn Schmiedebergs Arch Pharmacol
Main Authors: Szopa, Aleksandra, Poleszak, Ewa, Bogatko, Karolina, Wyska, Elżbieta, Wośko, Sylwia, Doboszewska, Urszula, Świąder, Katarzyna, Wlaź, Aleksandra, Dudka, Jarosław, Wróbel, Andrzej, Wlaź, Piotr, Serefko, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6208968/
https://ncbi.nlm.nih.gov/pubmed/30094458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-018-1551-z
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