MitoNEET-Parkin Effects in Pancreatic α- and β-Cells, Cellular Survival, and Intrainsular Cross Talk

Mitochondrial metabolism plays an integral role in glucose-stimulated insulin secretion (GSIS) in β-cells. In addition, the diabetogenic role of glucagon released from α-cells plays a major role in the etiology of both type 1 and type 2 diabetes because unopposed hyperglucagonemia is a pertinent con...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Kusminski, Christine M., Chen, Shiuhwei, Ye, Risheng, Sun, Kai, Wang, Qiong A., Spurgin, Stephen B., Sanders, Phillip E., Brozinick, Joseph T., Geldenhuys, Werner J., Li, Wen-hong, Unger, Roger H., Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2016
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310214/
https://ncbi.nlm.nih.gov/pubmed/26895793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db15-1323
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