What can mathematical modelling say about CHO metabolism and protein glycosylation?

Chinese hamster ovary cells have been in the spotlight for process optimization in recent years, due to being the major, long established cell factory for the production of recombinant proteins. A deep, quantitative understanding of CHO metabolism and mechanisms involved in protein glycosylation has...

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Bibliografiska uppgifter
I publikationen:Comput Struct Biotechnol J
Huvudupphovsmän: Galleguillos, Sarah N., Ruckerbauer, David, Gerstl, Matthias P., Borth, Nicole, Hanscho, Michael, Zanghellini, Jürgen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Research Network of Computational and Structural Biotechnology 2017
Ämnen:
Short Survey
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310201/
https://ncbi.nlm.nih.gov/pubmed/28228925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2017.01.005
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