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What can mathematical modelling say about CHO metabolism and protein glycosylation?

Chinese hamster ovary cells have been in the spotlight for process optimization in recent years, due to being the major, long established cell factory for the production of recombinant proteins. A deep, quantitative understanding of CHO metabolism and mechanisms involved in protein glycosylation has...

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Detalhes bibliográficos
Publicado no:Comput Struct Biotechnol J
Main Authors: Galleguillos, Sarah N., Ruckerbauer, David, Gerstl, Matthias P., Borth, Nicole, Hanscho, Michael, Zanghellini, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Research Network of Computational and Structural Biotechnology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310201/
https://ncbi.nlm.nih.gov/pubmed/28228925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.csbj.2017.01.005
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