DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

BACKGROUND: Lung disease progression is variable among cystic fibrosis (CF) patients and depends on DNA mutations in the CFTR gene, polymorphic variations in disease modifier genes, and environmental exposure. The contribution of genetic factors has been extensively investigated, whereas the mechani...

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發表在:Clin Epigenetics
Main Authors: Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, De Sario, Albertina
格式: Artigo
語言:Inglês
出版: BioMed Central 2017
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310067/
https://ncbi.nlm.nih.gov/pubmed/28289476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0300-8
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