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DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

BACKGROUND: Lung disease progression is variable among cystic fibrosis (CF) patients and depends on DNA mutations in the CFTR gene, polymorphic variations in disease modifier genes, and environmental exposure. The contribution of genetic factors has been extensively investigated, whereas the mechani...

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Detaylı Bibliyografya
Yayımlandı:Clin Epigenetics
Asıl Yazarlar: Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, De Sario, Albertina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310067/
https://ncbi.nlm.nih.gov/pubmed/28289476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0300-8
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