DNA methylation at modifier genes of lung disease severity is altered in cystic fibrosis

BACKGROUND: Lung disease progression is variable among cystic fibrosis (CF) patients and depends on DNA mutations in the CFTR gene, polymorphic variations in disease modifier genes, and environmental exposure. The contribution of genetic factors has been extensively investigated, whereas the mechani...

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Bibliografski detalji
Izdano u:Clin Epigenetics
Glavni autori: Magalhães, Milena, Rivals, Isabelle, Claustres, Mireille, Varilh, Jessica, Thomasset, Mélodie, Bergougnoux, Anne, Mely, Laurent, Leroy, Sylvie, Corvol, Harriet, Guillot, Loïc, Murris, Marlène, Beyne, Emmanuelle, Caimmi, Davide, Vachier, Isabelle, Chiron, Raphaël, De Sario, Albertina
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5310067/
https://ncbi.nlm.nih.gov/pubmed/28289476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-016-0300-8
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