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Targeted RNA-Seq profiling of splicing pattern in the DMD gene: exons are mostly constitutively spliced in human skeletal muscle

We have analysed the splicing pattern of the human Duchenne Muscular Dystrophy (DMD) NB transcript in normal skeletal muscle. To achieve depth of coverage required for the analysis of this lowly expressed gene in muscle, we designed a targeted RNA-Seq procedure that combines amplification of the ful...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Bougé, Anne-Laure, Murauer, Eva, Beyne, Emmanuelle, Miro, Julie, Varilh, Jessica, Taulan, Magali, Koenig, Michel, Claustres, Mireille, Tuffery-Giraud, Sylvie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206723/
https://ncbi.nlm.nih.gov/pubmed/28045018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep39094
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