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Small genomic insertions form enhancers that misregulate oncogenes
The non-coding regions of tumour cell genomes harbour a considerable fraction of total DNA sequence variation, but the functional contribution of these variants to tumorigenesis is ill-defined. Among these non-coding variants, somatic insertions are among the least well characterized due to challeng...
Shranjeno v:
izdano v: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Nature Publishing Group
2017
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5309821/ https://ncbi.nlm.nih.gov/pubmed/28181482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14385 |
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