Identification of the discontinuous binding site in human interleukin 1 beta for the type I interleukin 1 receptor.

Human interleukin 1 beta (IL-1 beta) exerts its diverse biological effects by binding to specific receptors on target cells. Two types of IL-1 receptor (IL-1R) have been identified: the type I IL-1R (p80) and the type II IL-1R (p68). Using site-specific mutagenesis, we have identified the binding si...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Labriola-Tompkins, E, Chandran, C, Kaffka, K L, Biondi, D, Graves, B J, Hatada, M, Madison, V S, Karas, J, Kilian, P L, Ju, G
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1837145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.24.11182
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