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Inactivation of GIRK channels weakens the pre‐ and postsynaptic inhibitory activity in dorsal raphe neurons

The serotonergic tone of the dorsal raphe (DR) is regulated by 5‐HT (1A) receptors, which negatively control serotonergic activity via the activation of G protein‐coupled inwardly rectifying K(+) (GIRK) channels. In addition, DR activity is modulated by local GABAergic transmission, which is believe...

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Pubblicato in:Physiol Rep
Autori principali: Llamosas, Nerea, Ugedo, Luisa, Torrecilla, Maria
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5309581/
https://ncbi.nlm.nih.gov/pubmed/28196855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.13141
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